Adaptive Interventions

Sequential, Multiple Assignment, Randomized Trial (SMART)

SAS code to compare embedded adaptive interventions

Supplementary Material

Software for informing the development of an Adaptive Intervention (Q-Learning)

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Data analysis method for using repeated continuous outcome measures from SMART studies to compare adaptive interventions.

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Linear mixed models for comparing adaptive interventions on a longitudinal outcome from SMART studies.

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Data analysis method for using longitudinal binary outcome data from SMART studies to compare adaptive interventions.

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Figures and Data

SMART sample size

Applet for calculating the minimum sample size for a pilot SMART

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Applet for calculating the minimum sample size for SMARTs with Binary or Continuous Outcomes

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Sample size calculation for comparing adaptive interventions in SMARTs with a continuous longitudinal outcome.

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Figures and Data

Sample size calculation and data analysis for comparing cluster-level adaptive interventions using data from SMART studies.

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Supplementary Material
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Just-in-Time Adaptive Interventions

Micro-Randomized trials (MRTs)

A sample size calculator for micro-randomized trials.

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R code for assessing time-varying causal effect moderation for analyzing data from an MRT.

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Data analysis method for assessing time-varying causal effect moderation in mobile health.

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Supplementary Material
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Additional Computer Code

The Substance Abuse Research Assistance (SARA) MRT: Workflow and templates for reproducing results.

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Engagement in a Digital World: Examples of Common Engagement Strategies

Online Supplement

Portions of this website and the related scientific research were funded by National Institute on Drug Abuse (NIDA) awards P50 DA039838 and P50 DA010075 to The Methodology Center at Penn State, Institute for Educational Sciences award R324B180003 and NIDA award R01 DA039901 to the University of Michigan.